Precursor T-lymphoblastic lymphoma presenting as primary renal lymphoma with acute renal failure
نویسندگان
چکیده
We report a case of acute renal failure (ARF) and bilateral nephromegaly in a patient with a history of Crohn's disease and treatment with azathioprine. Kidney biopsy revealed diffuse renal infiltration by precursor T-cell lymphoblastic lymphoma (T-LBL). At the time of diagnosis, no extrarenal manifestations of the lymphoma were detectable and therefore the lymphoma was categorized as primary renal lymphoma (PRL). Thus far, precursor T-LBL presenting as PRL has not been described before. We emphasize that in patients with ARF and bilateral renal enlargement, renal lymphoma is an important differential diagnostic consideration.
منابع مشابه
Acute renal failure due to renal lymphomatous infiltration as the initial manifestation
A male patient with acute renal failure (ARF) due to large B-cell non-Hodgkin lymphoma infiltration of kidney is presented. The diagnosis was suspected because of coincidence of ARF and tumor lysis syndrome non-responsive to conservative renal therapies. A renal biopsy confirmed diagnosis and appropriate chemotherapy led to complete improvement of renal function.
متن کاملMassively Enlarged Kidneys Due to Leukemic Infiltration in a Child
A few cases with bilateral renal enlargement in acute lymphoblastic leukemia were reported in literature. In this article, we reported an unusual case of a child with precursor B-ALL presenting with massively enlarged bilateral unobstructed kidneys and acute renal failure. Renal involvement of ALL should be taken into consideration in case with massively enlarged bilateral kidneys in radiologic...
متن کاملRenal Calculi: An Unusual Presentation of T-Cell Acute Lymphoblastic Leukemia.
Spontaneous tumor lysis syndrome is a rare initial presentation of hematologic malignancy in children that typically presents with complications of electrolyte derangement, specifically hyperkalemia, hyperphosphatemia, and hyperuricemia. We report a case of a 5-year-old boy who presented to the emergency department with gross hematuria, abdominal pain, and vomiting and was ultimately diagnosed ...
متن کاملSpontaneous Fatal Tumor Lysis Syndrome in a Patient with T-Cell Lymphoblastic Lymphoma/Leukemia: Successful Treatment with Continuous Renal Replacement Therapy and Increasing-Dose Gradually Chemotherapy
Tumor Lysis Syndrome (TLS) results from massive necrosis or apoptosis of large proliferating tumors and is characterized by marked hyper uricemia, hyperkalemia, and hyper phosphatemia secondary to cell lysis and the metabolism of excessive nucleic acids. Clinically significant TLS, with end-organ compromise, occurs in approximately 5% of all patients with hematologic malignancies and in up to 2...
متن کاملAcute lymphoblastic leukemia presenting as bilateral renal enlargement in a child.
OBJECTIVE To report a case with early presentation of acute lymphoblastic leukemia (ALL) as bilateral renal masses and renal failure. CLINICAL PRESENTATION AND INTERVENTION A 6-year-old boy was admitted with bilaterally enlarged kidneys and severe renal impairment. Magnetic resonance imaging (MRI) showed bilateral renal enlargement with features suggestive of an infiltrative lesion. According...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2011